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Chemical Structure : CCG 102487
Catalog No.: PC-62027Not For Human Use, Lab Use Only.
CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth.
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CCG 102487 is a CCG-2979 analog that reduces streptokinase (SK) activity with little inhibition of group A streptococcal (GAS) growth; alters the transcript level for key GAS virulence genes, including multiple adhesins (fibronectin binding proteins, collagen-like surface protein, laminin-binding surface protein, and M protein), cytolytic toxins (streptolysins O and S), secreted extracellular proteases (Mac, C5a peptidase, and SpeB), streptodornase Sda1 (DNase), complement inhibitor protein, and streptokinase.
| M.Wt | 428.594 | |
| Formula | C27H28N2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sun H, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.
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