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CID 9998128

Chemical Structure : CID 9998128

CAS No.: 733807-13-1

CID 9998128 (CID9998128)

Catalog No.: PC-35140Not For Human Use, Lab Use Only.

CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils; strongly binds to both amyloid beta 42 (Aβ42) fibrils and β-secretase and the van der Waals interaction is dominating over the electrostatic interaction in binding affinity.

Physicochemical Properties

M.Wt 352.401
Formula C21H16N6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine

References

1. Thai NQ, et al. ACS Chem Neurosci. 2018 May 18. doi: 10.1021/acschemneuro.8b00091.

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