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Chemical Structure : CMPD-1
Catalog No.: PC-70148Not For Human Use, Lab Use Only.
A potent, selective, non-ATP-competitive inhibitor of p38α-mediated MK2a phosphorylation with apparent Ki of 330 nM.
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A potent, selective, non-ATP-competitive inhibitor of p38α-mediated MK2a phosphorylation with apparent Ki of 330 nM; dose not prevents p38α-mediated phosphorylation of MBP and ATF-2; induces a significant G2/M arrest, also inhibits tubulin polymerization in glioblastoma cells.
| M.Wt | 349.4 | |
| Formula | C22H20FNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Davidson W, et al. Biochemistry. 2004 Sep 21;43(37):11658-71.
2. Gurgis F, et al. Cell Death Discov. 2015 Sep 7;1:15028.
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