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ChX0306710

Chemical Structure : ChX0306710

CAS No.:

ChX0306710 (ChX710)

Catalog No.: PC-63270Not For Human Use, Lab Use Only.

ChX710 (ChX0306710) is a small molecule that primes the type I interferon response to cytosolic DNA, which is dependent on the adaptor MAVS and IRF1, but not the IRF3.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ChX710 (ChX0306710) is a small molecule that primes the type I interferon response to cytosolic DNA, which is dependent on the adaptor MAVS and IRF1, but not the IRF3; induces Interferon-Stimulated Response Elements (ISRE) that is STING dependent, efficiently primes the interferon response to foreign DNA by potent synergistic effects on IFN-β secretion and ISG expression levels

Physicochemical Properties

M.Wt 323.4
Formula C18H21N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(1-(dimethylamino)propan-2-yl)-2-(pyridin-4-yl)-1H-benzo[d]imidazole-4-carboxamide

References

1. Khiar S, et al. Sci Rep. 2017 May 31;7(1):2561.

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