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Chemical Structure : Dafadine A
Catalog No.: PC-62248Not For Human Use, Lab Use Only.
Dafadine A is the first reported small-molecule DAF-9 cytochrome P450 inhibitor that robustly induces dauer formation in in the nematode Caenorhabditis elegans.
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Dafadine A is the first reported small-molecule DAF-9 cytochrome P450 inhibitor that robustly induces dauer formation in in the nematode Caenorhabditis elegans; also inhibits the mammalian ortholog of DAF-9 (CYP27A1); shows selectivity over CYP7A1 or CYP7B1.
| M.Wt | 391.463 | |
| Formula | C23H25N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Luciani GM, et al. Nat Chem Biol. 2011 Nov 6;7(12):891-3.
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