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Chemical Structure : EB‐42168
Catalog No.: PC-21888Not For Human Use, Lab Use Only.
EB‐42168 is a potent, selective G2019S-LRRK2 kinase inhibitor with IC50 of 1.1 nM (pS935-LRRK2) in FRET-based assay, >100-fold selective over WT-LRRR2.
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EB‐42168 is a potent, selective G2019S-LRRK2 kinase inhibitor with IC50 of 1.1 nM (pS935-LRRK2) in FRET-based assay, >100-fold selective over WT-LRRR2.
| M.Wt | 500.57 | |
| Formula | C25H28N10O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Albert W Garofalo, et al. J Med Chem. 2020 Dec 10;63(23):14821-14839.
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