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Enbezotinib

Chemical Structure : Enbezotinib

CAS No.: 2359649-81-1

Enbezotinib

Catalog No.: PC-73416Not For Human Use, Lab Use Only.

Enbezotinib is a potent, selective inhibitor of RET kinase, inhibits the RET autophosphorylation and shows antineoplastic activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Enbezotinib is a potent, selective inhibitor of RET kinase, inhibits the RET autophosphorylation and shows antineoplastic activity.
Enbezotinib (0.3-300 nM) inhibits p-RET (y905) in RET-driven cancer cell lines, suppresses tumor growth in vivo.

Physicochemical Properties

M.Wt 424.43
Formula C21H21FN6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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