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Chemical Structure : FR-901464
Catalog No.: PC-62420Not For Human Use, Lab Use Only.
FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases..
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FR-901464 is a potent antitumor natural product that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, inhibits cell cycle progression at G1 and G2/M phases.
| M.Wt | 507.616 | |
| Formula | C27H41NO8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Osman S, et al. Chemistry. 2011 Jan 17;17(3):895-904.
2. Albert BJ, et al. Mol Cancer Ther. 2009 Aug;8(8):2308-18.
3. Satoh T, et al. Sci Rep. 2016 Jun 10;6:27829.
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