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FR900098 sodium salt

Chemical Structure : FR900098 sodium salt

CAS No.: 73226-73-0

FR900098 sodium salt (FR 900098)

Catalog No.: PC-62608Not For Human Use, Lab Use Only.

FR 900098 is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FR 900098 is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.

Parasite Infection

Discontinued

Physicochemical Properties

M.Wt 219.109
Formula C5H11NNaO5P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

P-[3-(acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt

References

1. Jomaa H, et al. Science. 1999 Sep 3;285(5433):1573-6.

2. Reichenberg A, et al. Bioorg Med Chem Lett. 2001 Mar 26;11(6):833-5.

3. Okuhara M, et al. J Antibiot (Tokyo). 1980 Jan;33(1):13-7.

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