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Chemical Structure : GS-6207
CAS No.: 2189684-45-3
Catalog No.: PC-35869Not For Human Use, Lab Use Only.
GS-6207 (GS6207, GS-CA1, Lenacapavir) is a potent, selective inhibitor of HIV-1 capsid function with potency and potential to be clinically effective against a broad range of HIV-1 strains.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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GS-6207 (GS-CA1, Lenacapavir) is a potent, selective inhibitor of HIV-1 capsid function, shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
GS-6207 (GS-CA1, Lenacapavir) displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs).
GS-6207 (GS-CA1, Lenacapavir) has potency and potential to be clinically effective against a broad range of HIV-1 strains.
| M.Wt | 958.34 | |
| Formula | C41H36ClF8N7O5S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-((S)-1-(3-(4-chloro-3-(cyclopropanesulfonamido)-1-(2,2-difluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide |
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1. John O Link, et al. Nature. 2020 Jul 1.
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