GSK3987 | LXR agonist | Probechem Biochemicals

Chemical Structure : GSK3987

CAS No.: 264206-85-1

GSK3987 (GSK 3987)

Catalog No.: PC-38574Not For Human Use, Lab Use Only.

GSK3987 is a potent liver X receptor (LXR) agonist with EC50 of 50 nM and 40 nM for LXRα and LXRβ, respectively.

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Biological Activity

GSK3987 is a potent liver X receptor (LXR) agonist with EC50 of 50 nM and 40 nM for LXRα and LXRβ, respectively.
GSK3987recruits the steroid receptor coactivator-1 to human LXRα and LXRβ with EC50 of 40 nM in functional assays.

Physicochemical Properties

M.Wt	384.435
Formula	C24H20N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione

References

1. Jaye MC, et al. J Med Chem. 2005 Aug 25;48(17):5419-22.

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GSK3987 (GSK 3987)

Biological Activity

Physicochemical Properties

References

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