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HAP-12

Chemical Structure : HAP-12

CAS No.: 1078164-85-8

HAP-12 (HAP12)

Catalog No.: PC-63406Not For Human Use, Lab Use Only.

HAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

HAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.

Physicochemical Properties

M.Wt 444.891
Formula C22H22ClFN4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl 4-(2-chloro-4-fluorophenyl)-6-(morpholinomethyl)-2-(pyridin-2-yl)-1,4-dihydropyrimidine-5-carboxylate

References

1. Boucle S, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):904-910.

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