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Imagabalin hydrochloride

Chemical Structure : Imagabalin hydrochloride

CAS No.: 610300-00-0

Imagabalin hydrochloride (PD-0332334;PD-332334)

Catalog No.: PC-61834Not For Human Use, Lab Use Only.

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Imagabalin (PD 0332334) is a novel ligand for the α2δ subunit of the voltage-dependent calcium channel (VDCC) with some selectivity for the α2δ1 subunit over α2δ2; demonstrated preclinical efficacy of anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity for the treatment of generalized anxiety disorder.

Anxiety

Phase 3 Discontinued

Physicochemical Properties

M.Wt 209.714
Formula C9H20ClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3S,5R)-3-amino-5-methyloctanoic acid hydrochloride

References

1. Quintero JE, et al. Brain Res. 2011 Jul 15;1401:1-9.

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