Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Isomangiferin
CAS No.: 24699-16-9
Catalog No.: PN-30006Not For Human Use, Lab Use Only.
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $245 | In stock | |
| 10 mg | $345 | In stock | |
| 50 mg | $695 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.
| M.Wt | 422.3396 | |
| Formula | C19H18O11 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one |
|
1. Kang TH, et al. Eur J Pharmacol. 2002 Nov 22;455(1):27-34.
2. Kang TH, et al. Life Sci. 2004 Dec 3;76(3):331-43.
3. Fu AK, et al. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9959-64.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
