Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : J012-3168
Catalog No.: PC-20010Not For Human Use, Lab Use Only.
RPL11-MDM2 inhibitor S9 (J012-3168) is a small-molecule RPL11 mimetic and potential inhibitor of RPL11-MDM2 interaction, directly binds MDM2 and induces p53 stabilization and activation.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
RPL11-MDM2 inhibitor S9 (J012-3168) is a small-molecule RPL11 mimetic and potential inhibitor of RPL11-MDM2 interaction, directly binds MDM2 and induces p53 stabilization and activation.
S9 stabilizes p53 and increases p53 transcriptional activity.
S9 inhibits cancer cell proliferation in vitro and in vivo, induces cell cycle arrest and apoptosis.
| M.Wt | 376.42 | |
| Formula | C21H20N4O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Bingwu Wang, et al. Mol Med. 2022 Sep 7;28(1):109.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
