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Chemical Structure : JNJ-1A
Catalog No.: PC-35009Not For Human Use, Lab Use Only.
JNJ-1A is a novel Dengue virus (DENV) NS4B inhibitor that inhibits DENV-2 sub-genomic replicon at 0.7 μM, in the absence of cytotoxicity.
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JNJ-1A is a novel Dengue virus (DENV) NS4B inhibitor that inhibits DENV-2 sub-genomic replicon at 0.7 μM, in the absence of cytotoxicity; shows equipotent antiviral activity against DENV serotypes 1, 2, and 4, induces mutation T108I in non-structural protein 4B (NS4B) in in vitro resistance selection experiments.
| M.Wt | 761.942 | |
| Formula | C42H47N7O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hernandez-Morales I, et al. Antiviral Res. 2017 Nov;147:149-158.
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