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Chemical Structure : KDM-IN-6
Catalog No.: PC-61815Not For Human Use, Lab Use Only.
KDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively.
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KDM-IN-6 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM,respectively; displays >75 fold selectivity towards KDM2A/7A versus other JmjC lysine demethylase; shows cytotoxicity towards HeLa and HAP1 cells with EC50 of 22 uM and 7.1 uM respectively.
| M.Wt | 506.694 | |
| Formula | C33H38N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gerken P, et al. Angew Chem Int Ed Engl. 2017 Oct 4. doi: 10.1002/anie.201706788.
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