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LED-209

Chemical Structure : LED-209

CAS No.: 245342-14-7

LED-209 (LED 209;LED209)

Catalog No.: PC-45703Not For Human Use, Lab Use Only.

LED-209 is a bacterial conserved membrane histidine sensor kinase QseC inhibitor.

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10 mg $64 In stock
50 mg $256 In stock
100 mg $440 In stock

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Biological Activity

LED-209 is a bacterial conserved membrane histidine sensor kinase QseC inhibitor; prevents autophosphorylation and inhibits QseC-mediated activation of virulence gene expression; inhibits the virulence of several pathogens in vitro and in vivo in animals.

Physicochemical Properties

M.Wt 383.4872
Formula C19H17N3O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: < 3.8 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-

References

1. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80.

2. Spencer H, et al. J Bacteriol. 2010 Feb;192(3):714-24.

3. Xue XY, et al. Nanomedicine. 2015 Feb;11(2):329-39.

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