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Chemical Structure : LX-4211
CAS No.: 1018899-04-1
Catalog No.: PC-44486Not For Human Use, Lab Use Only.
A potent, selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $160 | In stock | |
| 25 mg | $360 | In stock | |
| 50 mg | $640 | In stock |
Bulk size, bulk discount!
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A potent, selective SGLT2 inhibitor with IC50 of 14 nM for hSGLT2; exhibits excellent selectivity over hSGLT1 (IC50=19 uM); inhibits SGLT2 in vitro and urinary glucose reabsorption in vivo.
Diabetes
Phase 2 Clinical
| M.Wt | 424.9382 | |
| Formula | C21H25ClO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
β-L-Xylopyranoside, methyl 5-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-thio-, (5S)- |
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1. Goodwin NC, et al. J Med Chem. 2009 Oct 22;52(20):6201-4.
2. Zambrowicz B, et al. Clin Pharmacol Ther. 2012 Aug;92(2):158-69.
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