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Chemical Structure : Leelamine hydrochloride
CAS No.: 16496-99-4
Catalog No.: PC-35497Not For Human Use, Lab Use Only.
Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 100 mg | $498 | In stock | |
| 500 mg | Get quote |
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Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells; causes apoptosis and suppresses 22Rv1 xenograft growth in vivo; Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.
| M.Wt | 321.933 | |
| Formula | C20H32ClN | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride |
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1. Singh KB, et al. Mol Cancer Ther. 2018 Jul 20. pii: molcanther.0117.2018.
2. Gowda R, et al. Oncotarget. 2017 Apr 25;8(17):28260-28277.
3. Sehrawat A, et al. Mol Carcinog. 2017 Feb;56(2):337-348.
4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul;13(7):1690-703.
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