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Chemical Structure : MB 07811
Catalog No.: PC-35609Not For Human Use, Lab Use Only.
MB 07811 (MB07811) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo.
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MB 07811 (MB07811) is an orally bioavailable, liver-targeted prodrug of MB07344, which is a thyroid hormone receptor-beta agonist (TRβ) agonist, efficiently converted to MB07344 by liver microsomes in vivo; reduces cholesterol and both serum and hepatic triglycerides at doses devoid of effects on body weight, glycemia, and the THA.
| M.Wt | 557.064 | |
| Formula | C31H38ClO5P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Erion MD, et al. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15490-5.
2. Ito BR, et al. Br J Pharmacol. 2009 Feb;156(3):454-65.
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