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Chemical Structure : ML-346
CAS No.: 100872-83-1
Catalog No.: PC-45512Not For Human Use, Lab Use Only.
A novel activator of HSP70 with EC50 of 4.6 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
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A novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.
| M.Wt | 272.2561 | |
| Formula | C14H12N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 29 mg/mL |
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| Chemical Name/SMILES |
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[3-(4-methoxyphenyl)-2-propen-1-ylidene]- |
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1. Calamini B, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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