Chemical Structure : NK-252
CAS No.: 1414963-82-8
Catalog No.: PC-45694Not For Human Use, Lab Use Only.
NK-252 is a novel Nrf2 activator.
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10 mg | $56 | In stock | |
25 mg | $120 | In stock | |
50 mg | $208 | In stock | |
100 mg | $384 | In stock |
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NK-252 is a novel Nrf2 activator; exhibits a greater Nrf2-activating potential than oltipraz (OPZ); interacts with the domain containing the Nrf2-binding site of Keap1; upregulates NQO1 gene expression and exerts antioxidant property in the liver of NASH model rats.
M.Wt | 285.2581 | |
Formula | C13H11N5O3 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 29 mg/mL |
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Chemical Name/SMILES |
Urea, N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)- |
1. Shimozono R, et al. Mol Pharmacol. 2013 Jul;84(1):62-70.
2. Kiue A, et al. Jpn J Cancer Res. 1990 Oct;81(10):1057-64.
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