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Chemical Structure : NU-7441
CAS No.: 503468-95-9
Catalog No.: PC-42782Not For Human Use, Lab Use Only.
NU-7441 (KU 57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | $488 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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NU-7441 (KU 57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM).
NU-7441 (KU 57788) also modestly inhibits BRD4 and BRDT with IC50 of 1 uM and 3.5 uM respectively.
NU-7441 (KU 57788) also stimulates Cas9-mediated genome editing.
| M.Wt | 413.4883 | |
| Formula | C25H19NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)- |
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1. Leahy JJ, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6083-7.
2. Robert F, et al. Genome Med. 2015 Aug 27;7:93.
3. Ember SW, et al. ACS Chem Biol. 2014 May 16;9(5):1160-71.
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