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ONO 2050297

Chemical Structure : ONO 2050297

CAS No.: 847655-65-6

ONO 2050297 (ONO-2050297;ONO2050297)

Catalog No.: PC-61097Not For Human Use, Lab Use Only.

ONO 2050297 (ONO2050297) is potent, selective, dual CysLT1 and CysLT2 antagonist with IC50 of 17 and 0.87 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ONO 2050297 (ONO2050297) is potent, selective, dual CysLT1 and CysLT2 antagonist with IC50 of 17 and 0.87 nM, respectively.

Physicochemical Properties

M.Wt 532.593
Formula C30H32N2O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-4-(3-carboxypropyl)-8-{[4-(4-phenylbutoxy)benzoyl]amino}-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

References

1. Itadani S, et al. ACS Med Chem Lett. 2014 Oct 6;5(11):1230-4.

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