Chemical Structure : PD-151746
CAS No.: 179461-52-0
Catalog No.: PC-45704Not For Human Use, Lab Use Only.
A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain.
Packing | Price | Stock | Quantity |
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10 mg | $80 | In stock | |
25 mg | $160 | In stock | |
50 mg | $256 | In stock | |
100 mg | $416 | In stock |
Bulk size, bulk discount!
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A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain; displays 20-fold selectivity over m-calpain; attenuates the SLLVY-AMC hydrolysis induced by maitotoxin in SY5Y cells; decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells.
M.Wt | 237.2501 | |
Formula | C11H8FNO2S | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 37 mg/mL |
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Chemical Name/SMILES |
2-Propenoic acid, 3-(5-fluoro-1H-indol-3-yl)-2-mercapto- |
1. Wang KK, et al. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
2. Porn-Ares MI, et al. Biochem J. 2003 Sep 1;374(Pt 2):403-11.
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