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PGC-1α  activator C80

Chemical Structure : PGC-1α activator C80

CAS No.: 154191-98-7

PGC-1α activator C80

Catalog No.: PC-62697Not For Human Use, Lab Use Only.

PGC-1α activator C80 is a potent PGC-1α acetylation activator with AC50 of 3.1 uM, induces Pck1 and G6pc expression with AC50 of 11.9 uM and 12.8 uM, reduces glucose production in hepatocytes..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PGC-1α activator C80 is a potent PGC-1α acetylation activator with AC50 of 3.1 uM, induces Pck1 and G6pc expression with AC50 of 11.9 uM and 12.8 uM, reduces glucose production in hepatocytes.

Physicochemical Properties

M.Wt 380.532
Formula C24H32N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(tert-butyl(4-methylbenzyl)amino)-3-((3-methyl-1H-indol-4-yl)oxy)propan-2-ol

References

1. Sharabi K, et al. Cell. 2017 Mar 23;169(1):148-160.e15.

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