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PI3Kα-IN-243

Chemical Structure : PI3Kα-IN-243

CAS No.: 1235449-52-1

PI3Kα-IN-243

Catalog No.: PC-45708Not For Human Use, Lab Use Only.

A potent PI3Kα inhibitor with IC50 of <0.1 uM.

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10 mg $400 In stock
50 mg $1200 In stock
100 mg $1680 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent PI3Kα inhibitor with IC50 of <0.1 uM; also inhibits HDAC (IC50=0.1-1 uM); compound 243 in patent US/20120088764A1.

Physicochemical Properties

M.Wt 507.5681
Formula C23H25N9O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 37 mg/mL

Chemical Name/SMILES

5-Pyrimidinecarboxamide, N-hydroxy-2-[methyl[[2-[6-(methylamino)-3-pyridinyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]amino]-

References

1. Patent US/20120088764A1

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