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Chemical Structure : PKCiota-IN-51
Catalog No.: PC-63488Not For Human Use, Lab Use Only.
PKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM, >15-fold selectivity over PKC-α and PKC-β.
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PKCiota-IN-51 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.7 nM, >15-fold selectivity over PKC-α and PKC-β; inhibits PKC-ι on the phosphorylation of substrate ECT2 in HCCLM3 cells with IC50 of 3.3 uM.
| M.Wt | 427.483 | |
| Formula | C25H22FN5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kwiatkowski J, et al. J Med Chem. 2018 May 4. doi: 10.1021/acs.jmedchem.8b00060.
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