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Chemical Structure : PRT-4165
CAS No.: 31083-55-3
Catalog No.: PC-45731Not For Human Use, Lab Use Only.
PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $158 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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PRT-4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation, inhibits the E3 ubiquitin ligase activity of PRC1, but not RNF8.
PRT-4165 inhibits double-strand breaks (DSBs) repair.
| M.Wt | 235.2375 | |
| Formula | C15H9NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)- |
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1. Ismail IH, et al. J Biol Chem. 2013 Sep 13;288(37):26944-54.
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