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Chemical Structure : Paricalcitol
CAS No.: 131918-61-1
Catalog No.: PC-45906Not For Human Use, Lab Use Only.
Paricalcitol is an analog of 1,25-dihydroxyergocalciferol that acts as a selective vitamin D receptor (VDR) activator.
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Paricalcitol is an analog of 1,25-dihydroxyergocalciferol that acts as a selective vitamin D receptor (VDR) activator.
Paricalcitol significantly decreases parathyroid hormone levels with no changes in calcium and phosphorous.
Paricalcitol also reduces serum concentrations of IL-6 and TNF-α compared to baseline; orally active.
| M.Wt | 416.6365 | |
| Formula | C27H44O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R,5Z)- |
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1. Donate-Correa J, et al. Nefrologia. 2017 Jun 13. pii: S0211-6995(17)30102-9.
2. Ritter C, et al. Kidney Int. 2017 Jul 24. pii: S0085-2538(17)30326-5.
3. Trohatou O, et al. J Cell Mol Med. 2017 Jun 29. doi: 10.1111/jcmm.13180.
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