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Paricalcitol

Chemical Structure Paricalcitol

CAS No.: 131918-61-1

Paricalcitol

Catalog No.: PC-45906Not For Human Use, Lab Use Only.

An analog of 1,25-dihydroxyergocalciferol that acts as a selective vitamin D receptor (VDR) activator.

Packing Price Stock Quantity
5 mg $480 In stock
10 mg $840 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

An analog of 1,25-dihydroxyergocalciferol that acts as a selective vitamin D receptor (VDR) activator; significantly decreases parathyroid hormone levels with no changes in calcium and phosphorous, also reduces serum concentrations of IL-6 and TNF-α compared to baseline; orally active.

Hyperparathyroidism

Approved

Physicochemical Properties

M.Wt 416.6365
Formula C27H44O3
CAS No. 131918-61-1
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

10 mM in DMSO

Chemical Name

1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3R,5Z)-

Clinical Information

References

1. Donate-Correa J, et al. Nefrologia. 2017 Jun 13. pii: S0211-6995(17)30102-9.

2. Ritter C, et al. Kidney Int. 2017 Jul 24. pii: S0085-2538(17)30326-5.

3. Trohatou O, et al. J Cell Mol Med. 2017 Jun 29. doi: 10.1111/jcmm.13180.

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