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Chemical Structure : Radalbuvir
Catalog No.: PC-63008Not For Human Use, Lab Use Only.
Radalbuvir (GS-9669) is a highly optimized thumb site II nonnucleoside inhibitor of HCV NS5B polymerase with binding affinity of 1.35 nM for genotype 1b.
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Radalbuvir (GS-9669) is a highly optimized thumb site II nonnucleoside inhibitor of HCV NS5B polymerase with binding affinity of 1.35 nM for genotype 1b.
Radalbuvir (GS-9669) shows inhibition of WT genotype 1b replicon and NS5B M423T mutant replicon with EC50 of 6 nM and 12 nM respectively.
| M.Wt | 543.719 | |
| Formula | C30H41NO6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lazerwith SE, et al. J Med Chem. 2014 Mar 13;57(5):1893-901.
2. Fenaux M, et al. Antimicrob Agents Chemother. 2013 Feb;57(2):804-10.
3. Dvory-Sobol H, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6599-606.
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