Chemical Structure : Runcaciguat
CAS No.: 1402936-61-1
Catalog No.: PC-36097Not For Human Use, Lab Use Only.
Runcaciguat is a potent soluble guanylyl cyclase (sGC) stimulator/activator, binds and activates oxidized and heme-free sGC and thereby restores NO-sGC-cGMP signaling under oxidative stress.
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Runcaciguat is a potent, selective soluble guanylyl cyclase (sGC) stimulator/activator, binds and activates oxidized and heme-free sGC and thereby restores NO-sGC-cGMP signaling under oxidative stress.
M.Wt | 488.328 | |
Formula | C23H22Cl2F3NO3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(3S)-3-{4-chloro-3-[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanamido]phenyl}-3-cyclopropylpropanoic acid |
1. PCT Int. Appl. (2018), WO 2018153899 A1 20180830.
2. PCT Int. Appl. (2012), WO 2012139888 A1 20121018.
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