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Chemical Structure : SL-0101
Catalog No.: PC-70183Not For Human Use, Lab Use Only.
The first specific inhibitor of RSK (p90 ribosomal S6 kinase) with IC50 of 89 nM for RSK2.
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The first specific inhibitor of RSK (p90 ribosomal S6 kinase) with IC50 of 89 nM for RSK2; does not inhibit upstream kinases such as MEK, Raf and PKC; inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.
| M.Wt | 516.46 | |
| Formula | C25H24O12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Smith JA, et al. Cancer Res. 2005 Feb 1;65(3):1027-34.
2. Flynn JM, et al. Am J Physiol Endocrinol Metab. 2008 Mar;294(3):E589-99.
3. Harada K, et al. J Biol Chem. 2010 Jul 30;285(31):24044-54.
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