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SR-16435

Chemical Structure : SR-16435

CAS No.: 857262-16-9

SR-16435 (SR16435)

Catalog No.: PC-61536Not For Human Use, Lab Use Only.

SR-16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SR-16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors; possesses analgesic activity with reduced tolerance development and diminished reward in mice.

Physicochemical Properties

M.Wt 338.495
Formula C22H30N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one

References

1. Khroyan TV, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):934-43.

2. Zaveri NT, et al. J Med Chem. 2004 Jun 3;47(12):2973-6.

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