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SR146131

Chemical Structure : SR146131

CAS No.: 221671-61-0

SR146131 (SR-146131;SR 146131)

Catalog No.: PC-35949Not For Human Use, Lab Use Only.

SR146131 (SR-146131) a small molecule positive allosteric modulator of the type 1 cholecystokinin receptor (CCK1R) with pEC50 of 10.34.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SR146131 (SR-146131) a small molecule positive allosteric modulator of the type 1 cholecystokinin receptor (CCK1R) with pEC50 of 10.34.

    Physicochemical Properties

    M.Wt 610.166
    Formula 551.695
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(2-((4-(4-chloro-2,5-dimethoxyphenyl)-5-(2-cyclohexylethyl)thiazol-2-yl)carbamoyl)-5,7-dimethyl-1H-indol-1-yl)acetic acid

    References

    1. Desai AJ, et al. Mol Pharmacol. 2018 Dec 27. pii: mol.118.114082. doi: 10.1124/mol.118.114082.

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