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Chemical Structure : SR 18292
CAS No.: 2095432-55-4
Catalog No.: PC-62696Not For Human Use, Lab Use Only.
SR 18292 (SR18292) is a potent PGC-1α acetylation activator that is similar to C-80, increases PGC-1α acetylation, suppresses gluconeogenic gene expression, and reduce glucose production in hepatocytes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 25 mg | $248 | In stock | |
| 100 mg | $658 | In stock | |
| 500 mg | Get quote |
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SR 18292 (SR18292) is a potent PGC-1α acetylation activator that is similar to C-80, increases PGC-1α acetylation, suppresses gluconeogenic gene expression, and reduce glucose production in hepatocytes; increases the interaction of PGC-1α with GCN5 and reduces transcriptional activity of HNF4α; reduces fasting blood glucose, increases hepatic insulin sensitivity, and improves glucose homeostasis in diabetic mice.
| M.Wt | 366.5 | |
| Formula | C23H30N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-[(1,1-dimethylethyl)[(4-methylphenyl)methyl]amino]-3-(1H-indol-4-yloxy)-2-propanol |
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1. Sharabi K, et al. Cell. 2017 Mar 23;169(1):148-160.e15.
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