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Chemical Structure : Samatasvir
Catalog No.: PC-61524Not For Human Use, Lab Use Only.
Samatasvir (IDX719) is a highly potent, selective inhibitor of HCV NS5A that effectively inhibits HCV genotype 1-5 replicons with EC50 of 2-24 pM.
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Samatasvir (IDX719) is a highly potent, selective inhibitor of HCV NS5A that effectively inhibits HCV genotype 1-5 replicons with EC50 of 2-24 pM; also retains full activity in the presence of HIV and hepatitis B virus (HBV) antivirals; demonstrates an overall additive effect when combined with IFN-α, ribavirin, representative HCV protease, and nonnucleoside polymerase inhibitors or the nucleotide prodrug IDX184.
HCV Infection
Phase 2 Clinical
| M.Wt | 885.062 | |
| Formula | C47H48N8O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bilello JP, et al. Antimicrob Agents Chemother. 2014 Aug;58(8):4431-42.
2. Vince B, et al. J Hepatol. 2014 May;60(5):920-7.
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