Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : TASP0315003
Catalog No.: PC-61459Not For Human Use, Lab Use Only.
A potent, selective, orally available GlyT1 inhibitor with IC50 of 1.6 nM, weakly inhibits rat GlyT2 (IC50=138 nM).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent, selective, orally available GlyT1 inhibitor with IC50 of 1.6 nM, weakly inhibits rat GlyT2 (IC50=138 nM); shows no activities at 107 other receptors, transporters, and ion channels, including NMDA, dopamine, serotonin and opioid receptors; significantly improves MK-801 impaired cognition, and also enhanced social memory in rats, reduces social interaction induced by repeated phencyclidine (PCP) in mice; also exhibits an antidepressant effect in rats, does not cause sedation or motor dysfunction.
| M.Wt | 491.943 | |
| Formula | C24H25ClF3N5O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
