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TBZE-029

Chemical Structure : TBZE-029

CAS No.: 246148-68-5

TBZE-029 (TBZE029)

Catalog No.: PC-62925Not For Human Use, Lab Use Only.

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

TBZE-029 is a selective inhibitor of the replication of several Enteroviruses with IC50 of 1.2 uM against coxsackievirus B3 replication, targets nonstructural protein 2C.

Physicochemical Properties

M.Wt 356.314
Formula C16H9F5N2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole

References

1. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.

2. De Palma AM, et al. Biochem Biophys Res Commun. 2007 Feb 16;353(3):628-32.

3. Aguado L, et al. J Med Chem. 2010 Jan 14;53(1):316-24.

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