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Chemical Structure : TH1834
Catalog No.: PC-60498Not For Human Use, Lab Use Only.
TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor.
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TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine.
TH1834 increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR.
TH1834 induces apoptosis and increases unrepaired DNA damage in breast cancer cells.
| M.Wt | 568.722 | |
| Formula | C33H40N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372.
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