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Chemical Structure : WIN-18446
CAS No.: 1477-57-2
Catalog No.: PC-60168Not For Human Use, Lab Use Only.
WIN-18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $78 | In stock | |
| 100 mg | $128 | In stock | |
| 200 mg | $198 | In stock | |
| 1 g | Get quote |
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WIN-18446 is a potent, covalent, orally active ALDH1A2 inhibitor with IC50 of 0.3 uM.
WIN-18446 potently inhibits spermatogenesis and causes infertility in vivo by inhibiting retinoic acid synthesis.
| M.Wt | 366.11 | |
| Formula | C12H20Cl4N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N,N'-1,8-Octanediylbis(2,2-dichloroacetamide) |
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1. Amory JK, et al. J Androl. 2011 Jan-Feb;32(1):111-9.
2. Paik J, et al. J Biol Chem. 2014 May 23;289(21):15104-17.
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