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Chemical Structure : XL-001
Catalog No.: PC-35625Not For Human Use, Lab Use Only.
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
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XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
XL-001 inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1.
XL-001 ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models.
| M.Wt | 438.586 | |
| Formula | C25H30N2O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhou L, et al. Kidney Int. 2018 Aug 6. pii: S0085-2538(18)30397-1.
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