Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Zanamivir
CAS No.: 139110-80-8
Catalog No.: PC-43395Not For Human Use, Lab Use Only.
Zanamivir is a hihly potent, broad-spetrum influenza viral neuraminidase (NA) inhibitor with IC50 of 0.95 nM and 2.7 nM for influenza A and B, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $98 | In stock | |
| 100 mg | $228 | In stock | |
| 250 mg | $368 | In stock | |
| 500 mg | $528 | In stock |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Zanamivir is a hihly potent, broad-spetrum influenza viral neuraminidase (NA) inhibitor with IC50 of 0.95 nM and 2.7 nM for influenza A and B, respectively; inhibits plaque formation by laboratory-passaged strains of influenza A and B viruses,IC50 ranging from 0.005 to 0.014 uM; interacts with a group of amino acids in the active site of neuraminidase, which are conserved in all influenza A and B strains. Zanamivir blocks the action of neuraminidase, which prevents the cleavage of sialic acid on the cell receptors, thus preventing release and spread of the newly formed virions.
Influenza
Approved
| M.Wt | 332.3098 | |
| Formula | C12H20N4O7 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
H2O: ≥ 33.33 mg/mL |
|
| Chemical Name/SMILES |
D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy- |
|
1. Woods JM, et al. Antimicrob Agents Chemother. 1993 Jul;37(7):1473-9.
2. Gubareva LV, et al. Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8.
3. McKimm-Breschkin JL, et al. Treat Respir Med. 2005;4(2):107-16.
4. Ryan DM, et al. Antimicrob Agents Chemother. 1994 Oct;38(10):2270-5.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
