| Cat. No. |
Product Name |
Information |
| PC-38857 |
Bentracimab
Anti-ticagrelor mAb
|
Bentracimab (PB2452) is a neutralizing monoclonal antibody fragment that binds the antiplatelet drug ticagrelor with high affinity, a ticagrelor reversal agent. |
| PC-38855 |
Barecetamab
Anti-ErbB3 mAb
|
Barecetamab (ISU 104) is a highly potent, fully human anti-ErbB3 monoclonal antibody, binds potently and specifically to the NRG1 binding region of domain 3 of ErbB3, exhibits potent antitumorigenic activity. |
| PC-38854 |
Bapotulimab
Anti-ILDR2 mAb
|
Bapotulimab (BAY 1905254) is a human/mouse/monkey cross-reactive antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2), blocks the immunosuppressive activity of ILDR2 for cancer immunotherapy. |
| PC-38853 |
Apitegromab
Anti-promyostatin mAb
|
Apitegromab (SRK-015) is a fully human anti-proMyostatin monoclonal antibody (mAb) of the immunoglobulin G4 (IgG4)/lambda isotype that specifically binds to human pro/latent myostatin with high affinity inhibiting myostatin activation. |
| PC-38852 |
Teclistamab
Anti-BCMA/CD3
|
Teclistamab (JNJ-64007957) is a BCMAxCD3 bispecific antibody, recruits and activates T cells to kill BCMA-expressing MM cells. |
| PC-38851 |
Alnuctamab
Anti-BCMA/CD3
|
Alnuctamab (CC-93269) is a T-cell redirecting bispecific antibody (BiTE) targeting BCMA for the treatment of multiple myeloma. |
| PC-38834 |
Ociperlimab
Anti-TIGIT mAb
|
Ociperlimab (BGB-A1217) is a novel humanized IgG1 anti-TIGIT antibody (mAb) with anti-tumor activities. |
| PC-38833 |
Obrindatamab
B7-H3/CD3 bispecific DART
|
Obrindatamab (Orlotamab, MGD009) is a Fc-bearing humanised bispecific dual-affinity re-targeting (DART) protein composed of Fv regions derived from monoclonal antibodies against the immunoregulatory protein B7-homologue 3 (B7-H3, CD276) and the T-cell surface antigen CD3, with potential immunostimulating and antineoplastic activities. |
| PC-38832 |
Mipasetamab
Anti-AXL mAb
|
Melrilimab (GSK3772847) is a humanized monoclonal antibody targeting oncoprotein AXL. Isotype: IgG1-kappa. Anti-[human AXL (AXL receptor tyrosine kinase, tyrosine-protein kinase receptor UFO)], humanized monoclonal antibody. |
| PC-38831 |
Melrilimab
Anti-IL1RL1 mAb
|
Melrilimab (GSK3772847) is a monoclonal antibody targeting interleukin-1 receptor-like 1 (IL1RL1 or ST2 or IL-33R), shows potential for treatment of asthma. |
| PC-38830 |
Letaplimab
Anti-CD47 mAb
|
Letaplimab (IBI 188) is a CD47 blocking monoclonal antibody that specifically block the CD47-SIRP-α axis, which transduces the "don't eat me" signal to macrophages. |
| PC-38827 |
Izuralimab
Anti PD1/ICOS bispecific mAb
|
Izuralimab (XmAb 23104, XmAb 104) is a bispecific monoclonal antibody targeting PD1 and ICOS (inducible T-cell costimulator, CD278), potentially resulting in enhanced anti-tumor immune response. |
