| Cat. No. |
Product Name |
Information |
| PC-24728 |
PF-4800567
CK1ε inhibitor
|
PF-4800567 is a potent, selective inhibitor of casein kinase 1 epsilon (CK1epsilon, CK1ε) with IC50 of 32 nM, >20-fold selectivity over CK1δ. |
| PC-24636 |
Chrysoeriol
CK2 inhibitor
|
Chrysoeriol is a natural product for CK2 (Casein kinase 2) inhibitor with IC50 of 0.5 uM, inhibits JAK2/STAT3, IκB/p65, and NF-κB pathways, shows strong anti-inflammatory activities. |
| PC-24635 |
FNH79
CK2 inhibitor
|
FNH79 is a highly selective and potent CK2 (Casein kinase 2) inhibitor with IC50 of 4 nM. |
| PC-24634 |
CK2A2 inhibitor 65
CK2A2 inhibitor
|
CK2A2 inhibitor 65 is a selective, brain-penetrant inhibitor of CK2A2 and CK2A2 with IC50 of 3 nM and 4 nM respectively. |
| PC-23901 |
PF670462 dihydrochloride
CK1ε/CK1δ inhibitor
|
PF-670462 dihydrochloride (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively. |
| PC-23900 |
MU1742
CK1 inhibitor
|
MU1742 is a potent, selective inhibitor of Casein kinases 1 (CK1) with IC50 of 7/6/28 nM for CK1α/CK1δ/CK1ε respectively, does not inhibit p38α. |
| PC-23588 |
Fam20C inhibitor 5k
Fam20C inhibitor
|
Fam20C inhibitor 5k is a potent small-molecule Fam20C inhibitor with IC50 of 2.1 uM, showspotent anti-proliferative activity against MDA-MB-231 and BT-549 cells with IC50 values of 11.8 uM and 9.7 uM, respectively. |
| PC-23106 |
CKIP-1 ligand C77
CKIP-1 ligand
|
CKIP-1 ligand C77 is a small molecule ligand of casein kinase 2 interacting protein-1 (CKIP-1) with SPR KD of 27.12 nM. |
| PC-22790 |
CX-5011
CK2 inhibitor
|
CX-5011 is a potent, selective inhibitor of protein kinase CK2 with IC50 of <10 nM, induces cell death by apoptosis and acts synergistically with imatinib or the MEK-inhibitor U0126 in imatinib-resistant CML cells. |
| PC-22407 |
SGC-CK2-2
CK2 inhibitor
|
SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945). |
| PC-22273 |
ARC-3140
CK2 inhibitor
|
ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22272 |
ARC-1502
CK2 inhibitor
|
ARC-1502 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 0.56 nM, addressing the ATP site and the substrate-binding site of CK2. interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
