| Cat. No. |
Product Name |
Information |
| PC-36021 |
GO289
CK2 inhibitor
|
GO289 (GO-289, GO 289) is a potent and selective inhibitor of casein kinase 2 (CK2) with IC50 of 7 nM in in vitro kinase assays, shows minor effects on CKIδ and CKIα activity in vitro. |
| PC-35629 |
BTX161
CK1α degrader
|
BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2. |
| PC-35628 |
Casein Kinase inhibitor A86
CK1α inhibitor, CDK7/9 inhibitor
|
Casein Kinase inhibitor A86 (CK1α inhibitor A86) is a novel pan-specific CK1 (CSNK1) inhibitor (Kd=1-10 nM, CK1α Kd=9.8 nM) that co-targets the transcriptional kinases CDK7 and CDK9, with hardly inhibition of CDK8, CDK13, CDK11a, CDK11b, and CDK19. |
| PC-35627 |
BTX-A51
CK1α inhibitor, CDK7/9 inhibitor
|
BTX-A51 (CK1α inhibitor A51) is a novel pan-specific CK1 (CSNK1) inhibitor (Kd=0.5-20 nM, CK1α Kd=5.3 nM) that co-targets the transcriptional kinases CDK7 and CDK9, with hardly inhibition of CDK8, CDK13, CDK11a, CDK11b, and CDK19. |
| PC-35616 |
BMS-699
CK2 inhibitor
|
BMS-699 (BMS699) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 0.1 nM (CKα). |
| PC-35614 |
BMS-595
CK2 inhibitor
|
BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα). |
| PC-35185 |
CAM4712
CK2α inhibitor
|
CAM4712 (CAM-4712) is a potent and selective CK2alpha (CK2α) inhibitor with IC50 of 7 uM, exhibits cell growth inhibition in HCT116 cell line with IC50 of 10 uM. |
| PC-35184 |
CAM4066
CK2α inhibitor
|
CAM4066 (CAM-4066) is a potent and selective CK2alpha (CK2α) inhibitor with Kd of 0.32 uM and IC50 of 0.37 uM, shows significantly improved selectivity compared to other CK2α inhibitors. |
| PC-43200 |
IC261
CK1δ/CK1ε inhibitor
|
IC261 (IC-261, SU-5607) is a potent, specific, ATP-competitive CK1delta/epsilon (CK1δ/CK1ε) with IC50 of 1 uM, does not block the activity of α, β and γ isoforms. |
| PC-62834 |
CK1-IN-3c
CK1δ/ε inhibitor
|
CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM. |
| PC-62346 |
CK2-IN-1
CK2 inhibitor
|
CK2-IN-1 is a potent, competitive inhibitor of ATP binding to Casein kinase 2 (CK2) with IC50 of 9 nM, induces differentiation of epidermal progenitor cells to terminally differentiated keratinocytes with EC50 of 0.1 uM. |
| PC-62192 |
Quinalizarin
CK2 inhibitor
|
Quinalizarin is a potent, selective and cell-permeable inhibitor of CK2 with Ki of 58 nM. |
