| Cat. No. |
Product Name |
Information |
| PC-73051 |
Procaspase-6 inhibitor 13
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM. |
| PC-73050 |
Procaspase-6 inhibitor 12
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM. |
| PC-73049 |
PG3d
Caspase-6 inhibitor
|
PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor. |
| PC-72960 |
NH-23-C2
Caspase-2 inhibitor
|
NH-23-C2 (Caspase-2 inhibitor NH-23-C2) is a potent, selective and cell-permeable endogenous caspase-2 inhibitor, does not block caspase-3 or caspase-8. |
| PC-35426 |
MALT1 paracaspase inhibitor 3
|
MALT1 paracaspase inhibitor 3 is a potent, specific, covalent inhibitor of MALT1 paracaspase with Ki of 10 nM, exhibits 10-and 100-fold improved potency in vitro and in vivo compared with Z-VRPR-fmk. |
| PC-63279 |
ML132
Caspase-1 inhibitor
|
ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.. |
| PC-42968 |
Q-VD-Oph
pan-Caspase inhibitor
|
Q-VD-Oph is a potent pan-caspase inhibitor, inhibits human recombinant caspase-7 with IC50 of 48 nM in cell-free assay, also inhibits caspase -1, 3, 8, 9, 10, and 12 with IC50 of 25-400 nM. |
| PC-62433 |
Emricasan
Caspase inhibitor
|
Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity. |
| PC-60171 |
KEA1-97
|
KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3. |
| PC-22034 |
CZL80
Caspase-1 inhibitor
|
Caspase-1 inhibitor CZL80 is a potent, selective, brain‐penetrable Caspase-1 inhibitor with IC50 of 0.01 uM. |
| PC-49742 |
NS3694
Apoptosis inhibitor
|
NS3694 (NS 3694) is a specific cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation, blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with IC50 of 50 uM. |
| PC-36043 |
MLT-747
|
MLT-747 (MLT747) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 14 nM. |
