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Request The Product List ofCdc2-like Kinase (CLK) Cdc2-like Kinase (CLK)

Cat. No. Product Name Information
PC-21433

CLK1 inhibitor 25

CLK inhibitor

CLK1 inhibitor 25 is a potent and selective inhibitor of cdc2-like kinase 1 (CLK1) with IC50 of 2 nM, 69-fold selective over DYRK1A.
PC-21432

SGC-CLK-1N

CLK inhibitor

SGC-CLK-1N (CAF-225) is the negative control compound of CLK1/2/4 inhibitor SGC-CLK-1 (CAF-170).
PC-21431

SGC-CLK-1

CLK inhibitor

SGC-CLK-1 (CAF-170) is a potent and selective inhibitor of Cdc2-Like kinases CLK1, 2 and 4 with binding IC50 values of 13 nM, 4 nM, and 46 nM, resepctively.
PC-20985

Leucettinib-92

DYRK/CLK inhibitor

Leucettinib-92 is a potent DYRK/CLK inhibitor, inhibits CLK1, CLK2, CLK4, DYRK1A and DYRK1B with IC50 of 9.2, 6, 6, 1.2 and 1.8 nM, respectively.
PC-20895

MW01

CLK inhibitor

MW01 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 360 and 14.1 nM, does not inhibit CLK3.
PC-20894

MW05

CLK inhibitor

MW05 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 1400 and 307 nM, does not inhibit CLK3.
PC-20756

ML315

CLK inhibitor

ML315 is a small molecule inhibitor of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases with IC50 of 68, 231, >10,000, 68, 282 and 1156 nM for CLK1/2/3/4 and DYRK1/2, respectively.
PC-20474

GPS192

CLK inhibitor

GPS192 (GPS 167) is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A.
PC-73374

CLK4 inhibitor 96

CLK4 inhibitor

CLK4 inhibitor 96 is a novel potent CLK4 inhibitor with IC50 of 57.5 nM.

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