| Cat. No. |
Product Name |
Information |
| PC-20169 |
AG-0029
D2/D3 agonist/H3 antagonist
|
AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM). |
| PC-20083 |
ABT-925
D3 receptor antagonist
|
ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. |
| PC-49576 |
(-)-GSK598809
D3R antagonist
|
GSK598809 (GSK-598809) is a potent, selective dopamine D(3) receptor antagonist with Ki value of 6.2 nM, >100-fold selectivity over D2 receptor. |
| PC-49304 |
ASP4345
D1R PAM
|
ASP4345 (ASP-4345) is a potent, selective positive allosteric modulator of the dopamine type 1 (D1) receptor that selectively binds to, and enhances the activity of, D1 receptors. |
| PC-49303 |
UCM-1306
D1R PAM
|
UCM-1306 (UCM1306) is a subtype-selective, non-covalent, orally bioavailable positive allosteric modulator of dopamine D1 receptor with EC50 of 60 nM. |
| PC-49149 |
(R)-ABS01-113
D3R antagonist
|
(R)-ABS01-113 is a potent, selective dopamine D3 receptor (D3R) antagonist with IC50 of 11.4 nM, binds with high affinity to D3R with Ki value of 0.34 nM. |
| PC-49148 |
(S)-ABS01-113
D3R agonist
|
(S)-ABS01-113 is a potent, highly selective and efficacious dopamine D3 receptor (D3R) partial agonist with EC50 of 7.6 nM, binds with high affinity to D3R with Ki value of 0.84 nM, >1,000-fold selectivity over D2R. |
| PC-49147 |
ABS01-113
D3R agonist
|
(±)-ABS01-113 is a structural analog of the D3R partial agonist, (±)-VK4-40. |
| PC-47115 |
Mesdopetam hemitartrate
D3R antagonist
|
Mesdopetam (IRL790) is a novel dopamine transmission modulator and dopamine D3 receptor antagonist with Ki/IC50 of 0.09/0.41 uM. |
| PC-47114 |
Mesdopetam
D3R antagonist
|
Mesdopetam (IRL790) is a novel dopamine transmission modulator and dopamine D3 receptor antagonist with Ki/IC50 of 0.09/0.41 uM. |
| PC-47104 |
BAK4-54
D3R antagonist
|
BAK4-54 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 8.0 nM as full D3R antagonist, EC50 of 140 nM as partial D3R agonist. |
| PC-47103 |
CAB2-015
D3R antagonist
|
CAB2-015 is a high affinity dopamine D3 receptor (D3R) antagonist/partial agonist withIC50 of 7.4 nM, Ki of 0.351 nM, 45-fold selectivity over D2R. |
